This cool DIY Nintendo arcade cabinet was made from the guys over at Instructables, using an old PC, a 17 inch LCD monitor, some plexiglass and some MDF.
Inside is an old PC and a 17″ LCD monitor. The back of the cabinet has two USB ports and two NES controller ports. You can connect regular, un-modded NES controllers and play with those or use the joystick and buttons on the control panel.
The front end is a simple VB program that auto loads when the PC boots. You never need to connect a mouse or keyboard to load your games. The VB program gives a list of games installed. Using the joystick, you can select the game you want to play.
Head on over to Instructables for full details on how to make your own DIY Nintendo Arcade Cabinet.